Application

Our cell-on-a-chip device can be seamlessly integrated with common laboratory instruments for a wide range of biological assays. Additionally, real-time cellular responses can be measured with our customer-exclusive visual imaging program.

Viability Assays

MTT, alamarBlueTM, Live/Dead stains

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Imaging with qualitative and semi-quantitative monitoring of cell morphology changes as cells respond to different stress conditions and treatments.

Biomarker Detection

qPCR, Mesoscale DiscoveryTM

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Quantification of mRNA levels or the release of biomarkers. For dry eye diseases, this includes cytokines of key inflammatory markers such as IL-6, IL-8, IL-1β, TNF-α, MMP-9, and MMP-1.

Protein expression

Immunoblot, Immunocytochemistry

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Quantification via immunoblot and visual detection through immunocytochemistry, such as DED-responsive proteins mucin-1 and ZO-1.

Cell Morphology

Time-lapse Microscopy

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Imaging with qualitative and semi-quantitative monitoring of cell morphology changes as cells respond to different stress conditions and treatments.

Cell-Cell Junctions

Fluoeoscein Staining

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Quantification of fluoroscein diffusion into cells through intercellular spaces.

Wound Healing

Scratch Assay

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Monitoring the cell migration towards the empty space/artificial wound using a scratch assay.

EyesoBio

Application