EyesoBio
Application
Our cell-on-a-chip device can be seamlessly integrated with common laboratory instruments for a wide range of biological assays. Additionally, real-time cellular responses can be measured with our customer-exclusive visual imaging program.
Viability Assays
MTT, alamarBlueTM, Live/Dead stains
Imaging with qualitative and semi-quantitative monitoring of cell morphology changes as cells respond to different stress conditions and treatments.
Biomarker Detection
qPCR, Mesoscale DiscoveryTM
Quantification of mRNA levels or the release of biomarkers. For dry eye diseases, this includes cytokines of key inflammatory markers such as IL-6, IL-8, IL-1β, TNF-α, MMP-9, and MMP-1.
Protein expression
Immunoblot, Immunocytochemistry
Quantification via immunoblot and visual detection through immunocytochemistry, such as DED-responsive proteins mucin-1 and ZO-1.
Cell Morphology
Time-lapse Microscopy
Imaging with qualitative and semi-quantitative monitoring of cell morphology changes as cells respond to different stress conditions and treatments.
Cell-Cell Junctions
Fluoeoscein Staining
Quantification of fluoroscein diffusion into cells through intercellular spaces.
Wound Healing
Scratch Assay
Monitoring the cell migration towards the empty space/artificial wound using a scratch assay.